Cancer Cell's 10th Anniversary Celebration - Looking Back By acheung Apr 8, 2002 Expression profiling improves risk assessment for pediatric ALL Article by Eng-Juh Yeoh, Mary E. Ross, James R. Downing and colleagues Apr 30, 2002 Dissecting p53 tumor suppressor functions in vivo Article by Clemens A. Schmitt, Scott W. Lowe and colleagues Aug 22, 2002 Stable suppression of tumorigenicity by RNA interference Report by Thijn R. Brummelkamp, René Bernards, and Reuven Agami Aug 25, 2002 BCR-ABL kinase domain mutations confer resistance to imatinib Article by Neil P. Shah, Charles L. Sawyers and colleagues Sep 19, 2002 Distinct BH3 domains promote apoptosis by different mechanisms Article by Anthony Letai, Stanley J. Korsmeyer and colleagues Apr 21, 2003 Hypoxia-induced Met activation drives tumor cell dissemination Article by Selma Pennacchietti, Paolo Michieli and colleagues Jun 23, 2003 A multigenic program mediating breast cancer metastasis to bone Article by Yibin Kang, Joan Massague and colleagues Sep 22, 2003 Pten null murine model for human prostate cancer Article by Shunyou Wang, Hong Wu and colleagues Oct 1, 2003 Puma mediates p53-dependent and –independent cell death Report by John R. Jeffers, Gerard P. Zambetti and colleagues Dec 10, 2003 Modeling and detecting ductal pancreatic cancer in mice Article by Sunil R. Hingorani, David A. Tuveson and colleagues Jun 3, 2004 HOXB13:IL17BR predicts relapse in early stage ER+ breast cancer Article by Xiao-Jun Ma, Mark G. Erlander, Dennis C. Sgroi and colleagues Jul 1, 2004 The LKB1 tumor suppressor negatively regulates mTOR signaling Article by Reuben Shaw, Lewis C. Cantley and colleagues Jul 19, 2004 Microenvironmental changes during breast tumor progression Article by Minna Allinen, Kornelia Polyak and colleagues Aug 23, 2004 Loss of PTEN predicts trastuzumab resistance Article by Yoichi Nagata, Keng-Hsueh Lan, Dihua Yu and colleagues Dec 20, 2004 Vascular normalization governs brain tumor response to radiation Article by Frank Winkler, Sergey V. Kozin, Rakesh K. Jain and colleagues Jan 17, 2005 Succinate conveys an oncogenic signal in TCA cycle-impaired cells Article by Mary A. Selak, Sean M. Armour, Eyal Gottlieb and colleagues Feb 14, 2005 Nilotinib, a selective inhibitor of native and mutant Bcr-Abl Article by Ellen Weisberg, Paul W. Manley, James D. Griffin and colleagues Mar 24, 2005 JAK2V617F mutations in myeloproliferative disorders Article by Ross L. Levine, Martha Wadleigh, Stephanie J. Lee, D. Gary Gilliland and colleagues May 16, 2005 B cells foster squamous carcinogenesis Article by Karin E. de Visser, Lidiya V. Korets and Lisa M. Coussens Sep 19, 2005 Tensional homeostasis and the malignant phenotype Article by Matthew J. Paszek, Nastaran Zahir, Valerie M. Weaver and colleagues Mar 13, 2006 Molecular subclasses of high-grade glioma Article by Heidi S. Phillips and colleagues Mar 13, 2006 MicroRNAs identify lung cancer histological types and prognosis Article by Nozomu Yanaihara, Curtis C. Harris and colleagues Jun 12, 2006 Epigenetic therapy upregulates microRNA expression Article by Yoshimasa Saito, Gangning Liang, Gerda Egger, Peter A. Jones and colleagues Nov 13, 2006 ABT-737 efficiently induces apoptosis if Mcl-1 is neutralized Article by Mark F. Van Delft, Andrew H. Wei, David C. S. Huang and colleagues Nov 13, 2006 Sensitivity and resistance to BH3 mimetic ABT-737 Article by Marina Konopleva, Michael Andreeff and colleagues Dec 11, 2006 A panel of cell lines models functional breast cancer subtypes Article by Richard M. Neve, Koei Chin, Joe W. Gray and colleagues Jan 15, 2007 Normalization of glioblastoma vasculature in patients Article by Tracy T. Batchelor, A. Gregory Sorensen, Rakesh K. Jain and colleagues Jan 15, 2007 A brain tumor stem cell niche Article by Christopher Calabrese, Richard J. Gilbertson and colleagues Mar 12, 2007 Molecular definition of breast tumor heterogeneity Article by Michail Shipitsin, Kornelia Polyak and colleagues Aug 13, 2007 Mutations in the noncanonical NF-kappaB pathway in MM Article by Jonathan J. Keats, Rafael Fonseca and colleagues Aug 13, 2007 Classical and alternative NF-kappaB pathways in multiple myeloma Article by Christina M. Annunziata, R. Eric Davis, Louis M. Staudt and colleagues Jan 7, 2008 Systemic spread in an early step in breast cancer Article by Yves Husemann, Jochen B. Geigl, Falk Schubert, Christoph A. Klein and colleagues Mar 10, 2008 HIF-1 regulated tumorigenesis by recruiting BMDCs Article by Rose Du, Kan V. Lu, Gabriele Bergers, and colleagues May 5, 2008 Myoepithelial control of breast tumor progression Article by Min Hu, Kornelia Polyak and colleagues Jul 7, 2008 Inhibition of premature senescence by Twist Article by Stephane Ansieau, Alain Puisieux and colleagues Jul 24, 2008 How cancer cells respond to antimitotic drugs Article by Karen E. Gasciogne and Stephen S. Taylor Feb 2, 2009 IL-6-Stat3 signaling in colitis-associated cancer Article by Sergei Grivennikov, Elaid Karin, Janos Terzic, Michael Karin and colleagues Mar 2, 2009 Brief antiangiogenic therapy increases metastasis Report by John M. L. Ebos, Robert S. Kerbel and colleagues Mar 2, 2009 Malignant progression in angiogenesis inhibition Article by Marta Paez-Ribes, Elizabeth Allen, Douglas Hanahan, Oriol Casanovas and colleagues Aug 3, 2009 Immune regulation of mammary cancer metastasis Article by David G. DeNardo, Lisa M. Coussens and colleagues Sep 8, 2009 Polarization of tumor-associated neutrophils by TGF-beta Article by Zvi G. Fridlender and colleagues Jan 19, 2010 Genomic Alterations in Clinical GBM Subtypes Article by Roel G. W. Verhaak, Katherine A. Hoadley, D. Neil Hayes and colleagues Feb 18, 2010 IDH1 and IDH2 Mutations in AML Generate 2HG Article by Patrick S. Ward, Craig B. Thompson and colleagues Apr 15, 2010 CpG Island Methylator Phenotype in Gliomas Article by Houtan Noushmehr, Daniel J. Weisenberger, Kristin Diefes, Peter W. Laird, Kenneth Aldape and colleagues Jun 24, 2010 Genomic Characterization of Human Prostate Cancers Article by Barry S. Taylor, Nikolaus Schultz, Haley Hieronymus, Charles L. Sawyers and colleagues Dec 2, 2010 IDH1/2 Mutations Perturb DNA Methylation in AML Article by Maria E. Figueroa, Omar Abdel-Wahab, Chao Lu, Craig B. Thompson, Ross L. Levine, Ari Melnick and colleagues Jan 6, 2011 AKT inhibition induces RTK expression Article by Sarat Chandarlapaty, Neal Rosen and colleagues Jan 18, 2011 2-HG is an antagonist of alpha-KG Article by Wei Xu, Hui Yang, Ying Liu, Kun-Liang Guan, Shi-min Zhao, Yue Xiong and colleagues Feb 3, 2011 Jagged1 promotes breast cancer bone metastasis Article by Nilay Senthi, Yibin Kang and colleagues Mar 8, 2011 SIRT3 reprograms cell metabolism through HIF1alpha Article by Lydia W. S. Finley, Marcia C. Haigis and colleagues Nov 15, 2011 Platelet-to-tumor cell signals promote metastasis Article by Miriam Labelle, Shahinoor Begum and Richard O. Hynes