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2700-3000 years ago was the first prosthetic from what we've found, it is from Ancient Egypt and made out of leather and wood
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The invention of the stethoscope by René Laennec had revolutionised diagnosing through amplifying the internal body sounds, such as your heart.
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The Discovery of X-rays by Wilhelm Roentgen helped transform medical imaging and diagnostics through X-waves.
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The first practical electrocardiogram by Willem Einthoven allowed electrical monitoring of heart function.
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The first formal biomedical engineering training marked the start of formal education in biomedical engineering.
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The first prosthetic heart valve implant was by Charles Hufnagel and helped advance cardiac surgery and prosthetic heart devices.
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The first successful open-heart surgery using a heart-lung machine by John H. Gibbon helped enable complex cardiac surgeries with circulatory support.
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The development of the first implantable cardiac pacemaker revolutionised the treatment of arrhythmias and heart block.
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The development of recombinant DNA technology helped lay the foundation for genetic engineering and biotechnology.
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The launch of the Human Genome Project enabled mapping of the entire human genome, revolutionising personalised medicine.